This small house was identified in the nineteenth century as the home of the Colombo family in the period from 1455 and 1470, when Cristoforo was growing up from the age of 4 till he was 9. It was certainly not a luxurious home: on the ground floor there are small spaces dedicated to a shop and kitchen, with a basin to collect water and a rudimentary latrine; upstairs, two small rooms, perhaps for eating and for the night.

The building was damaged during the bombing to which the “Sun King” subjected the city in 1684. It was the only one to be rebuilt, due to the importance of those who had lived there and subsequently surviving the widespread demolition that affected the area in the 1930s.

It is a small memorial to the great navigator, inside which displays and objects tell his story and, above all, recount his daily life.

The cloister of Sant’Andrea, after being dismantled in 1905, was relocated (in 1922) in the area adjacent to the Christopher Columbus' House, where it is possible to admire it today, albeit in a radically different context from the original. Its figured capitals are very suggestive and date to the mid-twelfth century, they were reused during the restructuring of 1294, together with others of a purely Gothic style.

Entering the cloister, you can see the angels on the corner capitals which, with their right hands raised, bless the entry. Those with the patience to search will find a capital, on one of the smaller columns on the right hand side, which bears a clear reference to the Genoese economic life of the Middle Ages: a caravan of mules with their packs.

Between 1900 and 1906 the monastry and parish church of Sant'Andrea della Porta, the oldest parts of which dated to the beginning of the year 1000, was completely demolished, together with the hill on which it stood, to allow the urban restructuring of the area and the construction of the building of the Bank of Italy.

The only part of the structure that was saved was the medieval cloister which was dismantled and relocated (about twenty years later) to its current location.

The cloister probably dates to the construction of the building itself or only a short time later, as evidenced by the original Romanesque style figured capitals, dating to the mid twelth century. However, it is likely that there was a substantial redevelopment towards the end of the thirteenth century: documents from 1294 refer to major works in which the older figured capitals were probably retained but others (in the Gothic style) were added, these are decorated with simple leaves.

In such an important city cross roads, and one with such symbolic importance, an image of the Madonna could hardly be left wanting, a figure to whom the Genoese were always particularly devoted - to the point of electing her as Queen in 1637.

Many "aedicule" in the alleys of the city host Marian images to which inhabitants and passers-by used to address prayers, invocations or simply brief thoughts. In the case of the one located at the Porta Soprana it depicts the Apparition of the Madonna della Guardia to Blessed Benedetto Pareto, an image which commemorates the event of 1490, when the Virgin appeared to a peasant in the hills north of Genoa. The author of the work is the Piedmontese Giovanni Grifo (Alba, 1869 - Genoa 1935) who uses the oil on slate technique.

The aedicule that houses it is earlier, dating to the 17th-18th centuries. To preserve the painting from the elements, it was replaced by a copy in 2015: the original is located in the entrance to the towers of Porta Soprana.

Two original engraved tablets dating from 1155, the year to which the construction of the monumental gate can therefore be dated, are built into the wall on the inside of the entrance gate.

One of them shows the names of the consuls under whose supervision the construction took place and, additionally, listing the Genoese victories in the West (Africa, Asia and Spain), making particular reference to Spain and the victories against the Moors in the cities of Tortosa and Almeria (1147 and 1148).

The second plaque, which is subsequent to this engraved cry of triumph, warns that: "If you bring peace you are allowed to touch these doors, if you seek war, you will return sad and defeated".

This magnificent gateway, surmounted by two towers, was the main access to the ancient city from the East (Levant).
Between 1155 and 1158, facing the threat of assault by the army of Frederick Barbarossa, the Genoese participated in the construction of the new city walls and gates. Thanks to this Genoa was not subjected to attack by the imperial troops and instead, the emperor was forced to negotiate with a city which was not only powerful, but also had a fleet capable of keeping any land army in check.
Restored in the early twentieth century, Porta Soprana impresses with the impetus of its towers but also with the elegance of the entrance arch: an ogival arch (which predates the adoption of this feature as a recurring motif of Gothic art) framed on both the interior and exterior by solid marble columns with  splendid decorated capitals.

The towers are closed to the public.